Well, as I wrote, SMBus is per definitionem a two-wire bus, there is no need to choose this. The only limitation is the permanently assigned pin SMBA, which is lost as a GPIO if you do not use SMBA, but can be placed on alternative GPIO positions. [see additional comment below]
The alert function is an optionally available function on the SMBus, with which the subordinate bus participants can inform the master about events. Alert has been added to the original definition of the SMBus module and can be used completely as required, i.e. with or without alert.
Pictures 283 and 284: it may look like a copy'n'paste at first glance, but only the module itself (the grey box) is identical, because the function is actually identical as well. Differences can then be found in the clock supply (I2C1 has a dedicated PCLK) and in the unfortunately somewhat irritating description. Figure 283 lists the designations I2C_*** on the right, which could be read as I2C0_***, while figure 284 lists I2C1, which is actually clearly different from I2C (=I2C0).
However, I agree with you that it would be less irritating if I2C_*** had been better called I2C1_*** in figure 283 and I2C1_*** had been better called I2C2_*** in figure 284.
Regards
/Peter
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