Is it possible to integrate any Middleware, any library which is not in STM32CubeMX data base into STM32CubeMX ?

[Cartu38 OpenDev]

Yes sounds possible relying on STM32PackCreator you can start from STM32CubeMX: https://www.st.com/resource/en/user_manual/dm00716911-how-to-create-a-software-pack-enhanced-for-stm32cubemx-using-stm32-pack-creator-tool-stmicroelectronics.pdf