Unable to toggle LED with respect to Timer Interrupts on STM32F411-re

I am new to this evaluation board, (Nucleo-64 STM32F411), I am working on timer , I need to Update event for every 1s and for every 1 s response from the Timer base I need to toggle the status of the LED.

In the following code I am not able to toggle the LED. I can't figure out what I am missing out with the code weather I need to update something on the code??

// ----------------------------------------------------------------------------
 
#include <stdio.h>
#include <stdlib.h>
#include "diag/Trace.h"
#include "stm32f4xx.h"
#include "stm32f4xx_hal_tim.h"
// ----------------------------------------------------------------------------
//
// Standalone STM32F4 empty sample (trace via DEBUG).
//
// Trace support is enabled by adding the TRACE macro definition.
// By default the trace messages are forwarded to the DEBUG output,
// but can be rerouted to any device or completely suppressed, by
// changing the definitions required in system/src/diag/trace_impl.c
// (currently OS_USE_TRACE_ITM, OS_USE_TRACE_SEMIHOSTING_DEBUG/_STDOUT).
//
 
// ----- main() ---------------------------------------------------------------
 
// Sample pragmas to cope with warnings. Please note the related line at
// the end of this function, used to pop the compiler diagnostics status.
#pragma GCC diagnostic push
#pragma GCC diagnostic ignored "-Wunused-parameter"
#pragma GCC diagnostic ignored "-Wmissing-declarations"
#pragma GCC diagnostic ignored "-Wreturn-type"
 
void init_periperalclock()
{
	 /* Enable GPIO clock */
	 RCC->AHB1ENR |= RCC_AHB1ENR_GPIOAEN; //Port A clock enable
 
	 /* Enable USART clock */
	 RCC->APB1ENR |= RCC_APB1ENR_TIM2EN; //TIM2 Enable
}
 
void init_gpiopins()
{
 
	/* GPIO Configurations for TIMER1 */
	GPIOA ->MODER |= GPIO_MODER_MODER0_1;// PA0 Timer channel 1
	GPIOA ->OTYPER|= 0;
	GPIOA ->OSPEEDR |= GPIO_OSPEEDER_OSPEEDR0_0;
	GPIOA ->PUPDR |= GPIO_PUPDR_PUPDR0_0 ;
	GPIOA ->AFR[0] |= 0x0001; // PA0 AFR value is AF01 so AFR[0] = 0x0001
 
	uint32_t position = 5;
	uint32_t temp = 0x00U;
 
	/* Configure IO Direction mode (Input, Output, Alternate or Analog) */
	temp = GPIOA->MODER; //0xa8000000 -- 10101000000000000000000000000000
	temp &= ~(GPIO_MODER_MODER0 << (position * 2U)); // 001111111111 // temp res = 0000000000000000000000000000000
	temp |= ((1 & 3) << (position * 2U)); // 10000000000
	GPIOA->MODER = temp; 	// temp res = 000000000000000000010000000000 // act data sheet val 1024 // GP Output mode
 
 
	/* Configure the IO Speed */
	temp = GPIOA->OSPEEDR; //0x0C000000 -- 1100000000000000000000000000
	temp &= ~(GPIO_OSPEEDER_OSPEEDR0 << (position * 2U)); // temp res = 00000000000000000000000000000000
	temp |= (2 << (position * 2U)); // 100000000000 // temp res = 00000000000000000000100000000000
	GPIOA->OSPEEDR = temp;
 
 
	/* Configure the IO Output Type */
	temp = GPIOA->OTYPER;
	temp &= ~(GPIO_OTYPER_OT_0 << position) ; // 01111 & 00000 --> 00000
	temp |= (((1 & 0x00000010U) >> 4U) << position); // ((0>>4)<<5)
	GPIOA->OTYPER = temp;
 
 
	/* Activate the Pull-up or Pull down resistor for the current IO */
	temp = GPIOA->PUPDR; //0x64000000 - 1100100000000000000000000000000
	temp &= ~(GPIO_PUPDR_PUPDR0 << (position * 2U)); // temp res = 00000000000000000000000000000000
	temp |= ((1) << (position * 2U)); //temp == 10000000000
	GPIOA->PUPDR = temp;
 
 
}
 
void init_timerConfiguration()
{
 
	TIM2 ->PSC = (uint16_t) (SystemCoreClock / 8000000) - 1;	//Setting up the pre-scalar value can be 1
 
	//Configure the Internal Clock source
	TIM2->SMCR &= ~TIM_SMCR_SMS; // Internal clock source
	TIM2-> CR1 |= TIM_CR1_CEN;
 
	//Select the up counter mode
	TIM2->CR1 |= TIM_COUNTERMODE_UP;
	TIM2->CR1 &= ~TIM_CR1_CKD;
 
	// Set the clock division to 1
	TIM2->CR1 |= TIM_CLOCKDIVISION_DIV1;
 
	//Set the Autoreload value
	TIM2->ARR = 49999;//PERIOD 
 
	// Generate an update event to reload the Prescaler value immediately
	TIM2->EGR = TIM_EGR_UG;
	TIM2->CCMR1 &= ~TIM_CCMR1_CC2S;
 
	TIM2 ->RCR |= ~TIM_RCR_REP;
 
	TIM2 ->SR = 0;
 
}
 
 
int
main(int argc, char* argv[])
{
 
init_periperalclock();
init_gpiopins();
init_timerConfiguration();
 
 // Infinite loop
 while (1)
 {
	 while((TIM2->SR & TIM_DIER_UIE))
	 {
		 GPIOA->ODR ^= GPIO_PIN_5;
	 }
 }
}
 
#pragma GCC diagnostic pop