Hi @nlaza.1​ and welcome to the Community :),
According to the RM0440 and precisely the comparator behavior in low-power modes table, the COMP registers are powered down and must be reinitialized after exiting Standby.
However, the sleep mode has no effect on the comparators.
But, the comparator interrupts cause the device to exit the Sleep mode.
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Thank you
Kaouthar
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