I would like the ability to generate an interrupt be programmed into the embedded flash so that I can use STHS34PF80 without a microcontroller. Is this possible?

I'd like to use STUSB4500 to allow for 20V 60+W to enter the system, but I'd also like to use the sideband pins (or other pins) to send some serial data to the host side. I'd like to know whether this is possible (seems like the chip doesn't use SBU ...