Hi @Amel NASRI​ ,I created a screen cast to demonstrate the issue. If you do not mind, watch the 3'30" clip to better understand this issue.Thanks, Sebastian

Hi @Amel NASRI​ ,Sure, *MX_DMA_INIT()* is called before *MX_SPI_INIT()* .What I do not understand is: Why does the debugger connection fails if the binary (which is to be uploaded to the device later) will enable SPI. Looks like a serious software is...