@BaiBai You should use latest Arduino IDE 2 version and use latest STM32 core 2.8.x.Then enable the "Optimize for Debugging" in the "Sketch" menu.After "upload", click on "Start Debugging" button and it should work. 

Hi @Andrew Neil STM32duino GitHub organization is a community project, it is not part of the official software ecosystem supported by ST. Nevertheless ST contributes to this community.For question, support, ..., you could submit a topic on the stm32d...

Hi @Driadix You should file an issue on the library:https://github.com/stm32duino/STM32SD/issues BR

Hi @2hg You should file an issue to the library:https://github.com/stm32duino/VL53L8CX  

USB CDC have to be enable to have the COM port.