The IRQ is appearing once the UART has sent something. Since you not seem to send anything the IRQ is not triggered.Check RM0016 page 363

Running 'ST Toolset.msi' did not work for me (both as normal user and admin) but I found my solution here:https://community.st.com/s/question/0D50X00009XkXhpSAF/stlink-v2-configuration-databaseIt says:You will need to open a command prompt in adminis...