Hi @RGima.1 ,
Yes it is possible as long as you are aligned with operating conditions described in product datasheet.
My confirmation is also based on the content of AN2566 Getting started with STM32F10xxx hardware development:
To improve conversion accuracy, the ADC has an independent power supply that can be filtered separately, and shielded from noise on the PCB.
- the ADC voltage supply input is available on a separate VDDA pin
- an isolated supply ground connection is provided on the VSSA pin
- On packages with 64 pins or less, the VREF+ and VREF- pins are not available, they are internally connected to the ADC voltage supply (VDDA) and ground (VSSA).
But in such case, you need also to pay attention to the details of the section "Power supply schemes": The VDDA pin must be connected to two external decoupling capacitors (100 nF Ceramic + 1 µF Tantalum or Ceramic).
And to complete my answer, I suggest you to have a look to AN2834 for tips on How to get the best ADC accuracy in STM32 microcontrollers.
-Amel
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