How is it possible to turn off the system tick related interrupt generation?
The SysTick counter runs on the processor clock. If this clock signal is stopped for low power mode, the SysTick counter stops.
Please refer to SysTick timer (STK) section in your related product Programming manual (PM0214) for more clarification.
If you are Cube user you can use the systick example from the firmware library that show how to use the default configuration of SysTick:
As a first thing, don't turn it on.
You can also
SysTick->CTRL = 0;
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