The 'F429 Disco with using a controller which supports both autonomous and "slave" functionality, showcases both the LTDC and LTDC-less operation. You might want the latter to save bandwidth on the internal buses of 'F4xx if your application is computationally intensive (and use the somewhat cheaper 'F427, and potentially save also the external SDRAM and pins to connect it, to counterweight the higher cost of the controller).
In other words, on this DISCO, you can easily try, whether your application is better off using LTDC or a TFT controller.
JW
